Tetrahydrofuran → HCID 178426548, compound

HRID 679631Notes

Reaction equation

HRID 679631 reaction equation
[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH:40]([N:41]([CH2:42][CH3:43])[CH:44]([CH3:45])[CH3:46])([CH3:47])[CH3:48].[Cl:1][c:2]1[c:3]([NH:9][c:10]2[nH:11][c:12]3[c:13]([n:14]2)[cH:15][c:16]([C:24](=[O:25])[OH:26])[c:17]2[c:18]3[CH2:19][C:20]([CH3:22])([CH3:23])[O:21]2)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[F:31][c:32]1[c:33]([NH2:34])[cH:35][cH:36][c:37]([CH3:39])[cH:38]1.[S:27]([Cl:28])([Cl:29])=[O:30]>>[Cl:1][c:2]1[c:3]([NH:9][c:10]2[nH:11][c:12]3[c:13]([n:14]2)[cH:15][c:16]([C:24](=[O:25])[NH:34][c:33]2[c:32]([F:31])[cH:38][c:37]([CH3:39])[cH:36][cH:35]2)[c:17]2[c:18]3[CH2:19][C:20]([CH3:22])([CH3:23])[O:21]2)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 24386Thionyl ChlorideHCID 679842-Fluoro-4-methylanilineHCID 81531DiisopropylethylamineHCID 178422813HCID 178422813, compound

Product 1

HCID 178426548HCID 178426548, compound

Sources & evidence

ORD record
ord-e7256e5375ae4591b6810aea687049ea
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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