反应详情

To a solution of (2E)-3-(4-chlorophenyl)prop-2-enoic acid (2.0 g, 11 mmol) in 50 mL methylene chloride was added oxalyl chloride (1.05 mL, 12.1 mmol) and N,N-dimethylformamide (0.05 mL, 0.6 mmol). The resulting mixture was stirred at r.t. for 6 h. The solvent was removed under vacuum. The resulting solid was diluted with hexanes and the solvent removed under vacuum to provide an off-white solid which was used without further purification.

1. customThe solvent was removed under vacuum
2. additionThe resulting solid was diluted with hexanes
3. customthe solvent removed under vacuum
4. customto provide an off-white solid which
5. customwas used without further purification