Tetrahydrofuran → 3-(4-piperidyl)-1H-indole

HRID 679835Notes

Reaction equation

HRID 679835 reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:31][CH2:32][O:33][C:34]([CH3:35])=[O:36].[N:1]1([c:7]2[cH:8][n:9]([Si:16]([CH:17]([CH3:18])[CH3:19])([CH:20]([CH3:21])[CH3:22])[CH:23]([CH3:24])[CH3:25])[c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]23)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[N:1]1([c:7]2[cH:8][nH:9][c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]23)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 589749863-Piperidin-1-yl-1-triisopropylsilanyl-1H-indole

Product 1

HCID 870923-(4-piperidyl)-1H-indole

Sources & evidence

ORD record
ord-9c9c32a698e645aba6a3d7c36ce8d1d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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