Tetrahydrofuran → trans-N-{4-[6-butyl-5-(4-cyclohexyloxy-phenyl)-pyridazin-3-yloxy]-cyclohexyl}-formamide
Reaction equation
[Al+3:40].[C:1]([CH3:3])([CH3:4])([O:5][C:6](=[O:2])[NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[n:16][n:17][c:18]([CH2:34][CH2:35][CH2:36][CH3:37])[c:19](-[c:21]3[cH:22][cH:23][c:24]([O:27][CH:28]4[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]4)[cH:25][cH:26]3)[cH:20]2)[CH2:12][CH2:13]1)[CH3:38].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[H-:39].[H-:42].[H-:43].[H-:44].[Li+:41]>>[O:5]=[CH:6][NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[n:16][n:17][c:18]([CH2:34][CH2:35][CH2:36][CH3:37])[c:19](-[c:21]3[cH:22][cH:23][c:24]([O:27][CH:28]4[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]4)[cH:25][cH:26]3)[cH:20]2)[CH2:12][CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c4cce96cc9944549a384064b4d2ffa6e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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