Dichloromethane → 4-[4-Amino-5-(2-methoxy-benzoyl)-pyrimidin-2-ylamino]-piperidine-1-carboxylic acid methyl ester
Reaction equation
[CH2:44]([Cl:45])[Cl:46].[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Cl:39][C:40](=[O:41])[O:42][CH3:43].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[NH2:8][c:9]1[n:10][c:11]([NH:25][CH:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[n:12][cH:13][c:14]1[C:15](=[O:16])[c:17]1[c:18]([O:23][CH3:24])[cH:19][cH:20][cH:21][cH:22]1>>[NH2:8][c:9]1[n:10][c:11]([NH:25][CH:26]2[CH2:27][CH2:28][N:29]([C:40](=[O:41])[O:42][CH3:43])[CH2:30][CH2:31]2)[n:12][cH:13][c:14]1[C:15](=[O:16])[c:17]1[c:18]([O:23][CH3:24])[cH:19][cH:20][cH:21][cH:22]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-eca3b3c97a134c93b8be6537a5cb3571
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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