Methyl iodide → 2-(6-Chloro-2,5-dimethylpyrimidin-4-yl)-2-(2,4,6-trimethylphenyl)-propionitrile
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:22][Si:23]([N-:24][Si:25]([CH3:26])([CH3:27])[CH3:28])([CH3:29])[CH3:30].[CH3:32][I:33].[Cl:1][c:2]1[c:3]([CH3:21])[c:4]([CH:9]([C:10]#[N:11])[c:12]2[c:13]([CH3:20])[cH:14][c:15]([CH3:19])[cH:16][c:17]2[CH3:18])[n:5][c:6]([CH3:8])[n:7]1.[Li+:31]>>[Cl:1][c:2]1[c:3]([CH3:21])[c:4]([C:9]([C:10]#[N:11])([c:12]2[c:13]([CH3:20])[cH:14][c:15]([CH3:19])[cH:16][c:17]2[CH3:18])[CH3:22])[n:5][c:6]([CH3:8])[n:7]1Participants
6
Sources & evidence
- ORD record
- ord-6edd4f5eb8b6488981fd07808d245ebe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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