Sodium ion → 3',5'-Dichloro-4'-(2-oxo-3-piperidin-1-yl-pyrrolidin-1-ylmethyl)-biphenyl-4-carboxylic acid methyl ester
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([Cl:22])[c:5]([CH2:6][N:7]2[C:8](=[O:18])[CH:9]([N:12]3[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]3)[CH2:10][CH2:11]2)[c:19]([Cl:21])[cH:20]1.[CH3:23][O:24][C:25](=[O:26])[c:27]1[cH:28][cH:29][c:30]([B:33]([OH:34])[OH:35])[cH:31][cH:32]1.[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[N:36]#[N:37].[Na+:45].[Na+:46].[O-:47][C:48](=[O:49])[O-:50].[cH:57]1[cH:58][cH:59][c:60]([P:61]([Pd:62]([P:63]([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)([P:82]([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[P:101]([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)([c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)([c:120]2[cH:121][cH:122][cH:123][cH:124][cH:125]2)[c:126]2[cH:127][cH:128][cH:129][cH:130][cH:131]2)[cH:132][cH:133]1>>[c:2]1(-[c:30]2[cH:29][cH:28][c:27]([C:25]([O:24][CH3:23])=[O:26])[cH:32][cH:31]2)[cH:3][c:4]([Cl:22])[c:5]([CH2:6][N:7]2[C:8](=[O:18])[CH:9]([N:12]3[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]3)[CH2:10][CH2:11]2)[c:19]([Cl:21])[cH:20]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-6b4b6a5b2f3c496db6ade8518b5262fe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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