Hydrochloric Acid → 4-(1H-Pyrazol-4-yl)-7-(2-(trimethylsilyl)ethoxy)methyl-7 H-pyrrolo(2,3-d)-pyrimidine

HRID 683121Notes

Reaction equation

HRID 683121 reaction equation
[CH2:1]([S:2]([N:3]1[CH2:4][C:5]([CH2:6][C:7]#[N:8])([n:10]2[n:11][cH:12][c:13](-[c:15]3[c:16]4[c:17]([n:18][cH:19][n:20]3)[n:21]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:29])([CH3:30])[CH3:31])[cH:22][cH:23]4)[cH:14]2)[CH2:9]1)(=[O:32])=[O:33])[CH3:34].[ClH:36].[Na+:38].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1.[OH-:37].[OH2:35]>>[nH:10]1[n:11][cH:12][c:13](-[c:15]2[c:16]3[c:17]([n:18][cH:19][n:20]2)[n:21]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:29])([CH3:30])[CH3:31])[cH:22][cH:23]3)[cH:14]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 578688652-(1-(Ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile

Product 1

HCID 426313464-(1H-Pyrazol-4-yl)-7-(2-(trimethylsilyl)ethoxy)methyl-7 H-pyrrolo(2,3-d)-pyrimidine

Sources & evidence

ORD record
ord-371c06af0c094b85a0eb34354877e58c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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