Hydrochloric Acid → [2-(2,6-Dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine

HRID 683169Notes

Reaction equation

HRID 683169 reaction equation
[CH:32]([OH:33])([CH3:34])[CH3:35].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]([CH2:11][c:12]1[c:13]([Cl:19])[cH:14][cH:15][cH:16][c:17]1[Cl:18])[n:10]2.[ClH:31].[F:20][C:21]([c:22]1[cH:23][cH:24][c:25]([NH2:28])[cH:26][cH:27]1)([F:29])[F:30]>>[c:2]1([NH:28][c:25]2[cH:24][cH:23][c:22]([C:21]([F:20])([F:29])[F:30])[cH:27][cH:26]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]([CH2:11][c:12]1[c:13]([Cl:19])[cH:14][cH:15][cH:16][c:17]1[Cl:18])[n:10]2

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 3776IsopropanolHCID 99644-(Trifluoromethyl)anilineHCID 577424637-Chloro-2-(2,6-dichloro-benzyl)-thiazolo[5,4-d]pyrimidine

Product 1

HCID 42642137[2-(2,6-Dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine

Sources & evidence

ORD record
ord-54a584e34ada40c5bbad28960e35e1ba
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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