2-Aminothiazole → tert-Butyl 4-(2-oxo-2-(thiazol-2-ylamino)ethyl)piperazine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][C:15](=[O:16])[OH:17])[CH2:12][CH2:13]1.[CH:24]([N:25]([CH:26]([CH3:27])[CH3:28])[CH2:29][CH3:30])([CH3:31])[CH3:32].[Cl:66][CH2:67][Cl:68].[NH2:18][c:19]1[s:20][cH:21][cH:22][n:23]1.[P-:33]([F:34])([F:35])([F:36])([F:37])([F:38])[F:39].[n:40]1([O:41][P+:42]([N:43]2[CH2:44][CH2:45][CH2:46][CH2:47]2)([N:48]2[CH2:49][CH2:50][CH2:51][CH2:52]2)[N:53]2[CH2:54][CH2:55][CH2:56][CH2:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][c:63]2[n:64][n:65]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][C:15](=[O:17])[NH:18][c:19]2[s:20][cH:21][cH:22][n:23]2)[CH2:12][CH2:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-0817fda19b3d4b6c8633f5fadbf022ab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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