Tetrahydrofuran → 4-Amino-N-(1-azabicyclo[2.2.2]oct-3-yl)-5-chloro-2-[(3-chlorophenyl)methoxy]benzamide
Reaction equation
[C:21]([n:22]1[cH:23][cH:24][n:25][cH:26]1)([n:27]1[cH:28][cH:29][n:30][cH:31]1)=[O:32].[NH2:1][c:2]1[cH:3][c:4]([O:12][CH2:13][c:14]2[cH:15][c:16]([Cl:20])[cH:17][cH:18][cH:19]2)[c:5]([C:6](=[O:7])[OH:8])[cH:9][c:10]1[Cl:11].[NH2:33][CH:34]1[CH2:35][N:36]2[CH2:37][CH2:38][CH:39]1[CH2:40][CH2:41]2.[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[NH2:1][c:2]1[cH:3][c:4]([O:12][CH2:13][c:14]2[cH:15][c:16]([Cl:20])[cH:17][cH:18][cH:19]2)[c:5]([C:6](=[O:8])[NH:33][CH:34]2[CH2:35][N:36]3[CH2:37][CH2:38][CH:39]2[CH2:40][CH2:41]3)[cH:9][c:10]1[Cl:11]Participants
5
Sources & evidence
- ORD record
- ord-df4016be84eb42cb8abb923d3b83edcd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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