Benzene → 2-Amino-5-chloro-3-fluoro-6-(p-methoxybenzylamino)pyridine
Reaction equation
[CH3:18][O:19][c:20]1[cH:21][cH:22][c:23]([CH2:24][NH2:25])[cH:26][cH:27]1.[CH3:1][N:2]1[CH2:3][CH2:4][CH2:5][C:6]1=[O:7].[CH3:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39].[NH2:8][c:9]1[n:10][c:11]([F:17])[c:12]([Cl:16])[cH:13][c:14]1[F:15].[cH:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[NH2:8][c:9]1[n:10][c:11]([NH:25][CH2:24][c:23]2[cH:22][cH:21][c:20]([O:19][CH3:18])[cH:27][cH:26]2)[c:12]([Cl:16])[cH:13][c:14]1[F:15]Participants
6
Sources & evidence
- ORD record
- ord-7b03600d16224698a8c5377329e92ab3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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