Tetrahydrofuran → HCID 68953198, compound

HRID 683963Notes

Reaction equation

HRID 683963 reaction equation
[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:39][O:40][c:41]1[c:42]([C:50]([F:51])([F:52])[F:53])[cH:43][c:44]([C:45](=[O:46])[Cl:47])[cH:48][cH:49]1.[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:1][c:2]1[cH:3][c:4]([CH:9]2[CH2:10][N:11]([C:16](=[O:17])[CH:18]3[CH2:19][CH2:20][N:21]([C:24](=[O:25])[C:26]4([CH3:29])[CH2:27][CH2:28]4)[CH2:22][CH2:23]3)[CH2:12][CH:13]2[NH:14][CH3:15])[cH:5][cH:6][c:7]1[Cl:8]>>[Cl:1][c:2]1[cH:3][c:4]([CH:9]2[CH2:10][N:11]([C:16](=[O:17])[CH:18]3[CH2:19][CH2:20][N:21]([C:24](=[O:25])[C:26]4([CH3:29])[CH2:27][CH2:28]4)[CH2:22][CH2:23]3)[CH2:12][CH:13]2[N:14]([CH3:15])[C:45]([c:44]2[cH:43][c:42]([C:50]([F:51])([F:52])[F:53])[c:41]([O:40][CH3:39])[cH:49][cH:48]2)=[O:46])[cH:5][cH:6][c:7]1[Cl:8]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 81531DiisopropylethylamineHCID 27752984-Methoxy-3-(trifluoromethyl)benzoyl chlorideHCID 67025815[(3SR,4RS)-3-(3,4-Dichloro-phenyl)-4-methylamino-pyrrolidin-1-yl]-[1-(1-methyl-cyclopropanecarbonyl)-piperidin-4-yl]-methanone

Product 1

HCID 68953198HCID 68953198, compound

Sources & evidence

ORD record
ord-a6fb35456cc44b81930cf717d4b5b8c3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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