Ethyl Acetate → ethyl [4-bromo-3-(4,5-difluoro-2-hydroxyphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate
Reaction equation
[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[N:6]([CH2:11][C:12](=[O:13])[O:14][CH2:15][CH3:16])[C:5](=[O:17])[C:4]2([OH:18])[c:19]1[c:20]([OH:27])[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]1.[CH2:28]([SiH:29]([CH2:30][CH3:31])[CH2:32][CH3:33])[CH3:34].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40]>>[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[N:6]([CH2:11][C:12](=[O:13])[O:14][CH2:15][CH3:16])[C:5](=[O:17])[CH:4]2[c:19]1[c:20]([OH:27])[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]1Participants
4
Sources & evidence
- ORD record
- ord-8f8206b268944695a205c73359b5fe34
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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