Dimethylformamide → 5-(4-chlorophenyl)-N-(2-hydroxycyclohexyl)-6-(3-methoxyprop-1-ynyl)pyridine-3-carboxamide
Reaction equation
[CH3:2][O:3][CH2:4][C:5]#[CH:6].[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[Cl:7][c:8]1[n:9][cH:10][c:11]([C:12](=[O:13])[NH:14][CH:15]2[CH:16]([OH:21])[CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:22][c:23]1-[c:24]1[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]1.[I-:1].[Pd:36]([Cl:37])[Cl:38].[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1.[c:58]1([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[cH:72][cH:73][cH:74][cH:75][cH:76]1>>[CH3:2][O:3][CH2:4][C:5]#[C:6][c:8]1[n:9][cH:10][c:11]([C:12](=[O:13])[NH:14][CH:15]2[CH:16]([OH:21])[CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:22][c:23]1-[c:24]1[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-cba9f7b1c4b944eabcdcc6dd16fc4442
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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