Ethanol → [4-[(2-Chloro-4,4-difluoro-spiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-1-(3-chloro-2-pyridyl)pyrazol-3-yl]methanol
Reaction equation
[BH4-:36].[CH3:43][CH2:44][OH:45].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([s:6]1)[C:7]1([CH2:8][CH2:9][N:10]([CH2:13][c:14]3[c:15]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[n:16][n:17](-[c:19]4[n:20][cH:21][cH:22][cH:23][c:24]4[Cl:25])[cH:18]3)[CH2:11][CH2:12]1)[O:31][CH2:32][C:33]2([F:34])[F:35].[Li+:37].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([s:6]1)[C:7]1([CH2:8][CH2:9][N:10]([CH2:13][c:14]3[c:15]([CH2:26][OH:27])[n:16][n:17](-[c:19]4[n:20][cH:21][cH:22][cH:23][c:24]4[Cl:25])[cH:18]3)[CH2:11][CH2:12]1)[O:31][CH2:32][C:33]2([F:34])[F:35]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-df9038e89a6943028ea3023e2a443ffb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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