HRID684636

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

HCID81531

Diisopropylethylamine

C8H19N

HCID2737531

4-Amino-1-methylpiperidine

C6H14N2

结构：Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2OC(C)(C)CO)C12C(=O)Nc1cc(Cl)ccc12

HCID76567885

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2OC(C)(C)C(=O)NC2CCN(C)CC2)C12C(=O)Nc1cc(Cl)ccc12

HCID74928666

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d3778ec5f3f1447889d466b317491178
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (3/10)

反应 SMILES

[CH2:66]1[O:67][CH2:68][CH2:69][CH2:70]1.[CH3:58][N:59]1[CH2:60][CH2:61][CH:62]([NH2:65])[CH2:63][CH2:64]1.[CH:49]([N:50]([CH2:51][CH3:52])[CH:53]([CH3:54])[CH3:55])([CH3:56])[CH3:57].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:31]2[c:32]([CH3:38])[cH:33][cH:34][c:35]([F:37])[cH:36]2)[NH:13][C:14](=[O:30])[CH2:15][CH:16]1[c:17]1[c:18]([O:24][C:25]([CH2:26][OH:27])([CH3:28])[CH3:29])[cH:19][cH:20][c:21]([Cl:23])[cH:22]1.[OH:39][n:40]1[c:41]2[c:42]([cH:43][cH:44][cH:45][cH:46]2)[n:47][n:48]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:31]2[c:32]([CH3:38])[cH:33][cH:34][c:35]([F:37])[cH:36]2)[NH:13][C:14](=[O:30])[CH2:15][CH:16]1[c:17]1[c:18]([O:24][C:25]([C:26](=[O:27])[NH:65][CH:62]2[CH2:61][CH2:60][N:59]([CH3:58])[CH2:64][CH2:63]2)([CH3:28])[CH3:29])[cH:19][cH:20][c:21]([Cl:23])[cH:22]1