Dimethylformamide → N-[4-(diethylphosphonomethyl)phenyl]-3-[5-(4-trifluoromethylphenyl)-4-isoxazolyl]propionamide
Reaction equation
[CH2:47]([N:48]=[C:49]=[N:50][CH2:51][CH2:52][CH2:53][N:54]([CH3:55])[CH3:56])[CH3:57].[CH3:58][N:59]([CH3:60])[CH:61]=[O:62].[F:17][C:18]([c:19]1[cH:20][cH:21][c:22](-[c:25]2[c:26]([CH2:30][CH2:31][C:32](=[O:33])[OH:34])[cH:27][n:28][o:29]2)[cH:23][cH:24]1)([F:35])[F:36].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][P:7]([O:8][CH2:9][CH3:10])([O:11][CH2:12][CH3:13])=[O:14])[cH:15][cH:16]1.[OH:37][n:38]1[c:39]2[n:40][cH:41][cH:42][cH:43][c:44]2[n:45][n:46]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH2:6][P:7]([O:8][CH2:9][CH3:10])([O:11][CH2:12][CH3:13])=[O:14])[cH:15][cH:16]1)[C:32]([CH2:31][CH2:30][c:26]1[c:25](-[c:22]2[cH:21][cH:20][c:19]([C:18]([F:17])([F:35])[F:36])[cH:24][cH:23]2)[o:29][n:28][cH:27]1)=[O:33]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-53832dcc7000488ca7973b8339a87ab4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…