Dimethylformamide → cis-(4-Isopropyl-piperazin-1-yl)-(4-hydroxycyclohexyl)-methanone
Reaction equation
[B-:20]([F:21])([F:22])([F:23])[F:24].[CH3:42][CH2:43][N:44]([CH2:45][CH3:46])[CH2:47][CH3:48].[CH:11]([CH3:12])([CH3:13])[N:14]1[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]1.[O:49]=[CH:50][N:51]([CH3:52])[CH3:53].[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([C:8](=[O:9])[OH:10])[CH2:6][CH2:7]1.[n:25]1([O:26][C:27]([N:28]([CH3:29])[CH3:30])=[N+:31]([CH3:32])[CH3:33])[c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]2[n:40][n:41]1>>[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([C:8](=[O:10])[N:17]2[CH2:16][CH2:15][N:14]([CH:11]([CH3:12])[CH3:13])[CH2:19][CH2:18]2)[CH2:6][CH2:7]1Participants
7
Sources & evidence
- ORD record
- ord-52abca9f1f1a41a19291d25220350445
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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