Ammonia → 4-{1-(4-Fluorophenyl)-2-[4-(naphthalen-1-yl-butyl)piperazin-1-yl]ethyl}-1-methylpiperidin-4-ol
Reaction equation
[Al+3:40].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([CH2:17][CH2:18][CH2:19][CH2:20][c:21]3[cH:22][cH:23][cH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]34)[CH2:15][CH2:16]2)[C:31]2([OH:38])[CH2:32][CH2:33][N:34]([CH3:37])[CH2:35][CH2:36]2)[cH:6][cH:7]1.[H-:39].[H-:42].[H-:43].[H-:44].[Li+:41].[NH3:50].[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][N:11]2[CH2:12][CH2:13][N:14]([CH2:17][CH2:18][CH2:19][CH2:20][c:21]3[cH:22][cH:23][cH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]34)[CH2:15][CH2:16]2)[C:31]2([OH:38])[CH2:32][CH2:33][N:34]([CH3:37])[CH2:35][CH2:36]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-3241e1364b2744ce974588a529fb84b9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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