Dimethylformamide → 1-butyl-3-chloro-4-hydroxy-2(1H)-Pyridinone

HRID 685128Notes

Reaction equation

HRID 685128 reaction equation
[CH2:9]([CH2:10][CH2:11][CH3:12])[n:13]1[c:14](=[O:20])[cH:15][c:16]([OH:19])[cH:17][cH:18]1.[CH:21]1([CH2:22][n:23]2[cH:24][cH:25][c:26]([OH:27])[cH:28][c:29]2=[O:30])[CH2:31][CH2:32]1.[Cl:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37]>>[Cl:1][c:15]1[c:14](=[O:20])[n:13]([CH2:9][CH2:10][CH2:11][CH3:12])[cH:18][cH:17][c:16]1[OH:19]

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 31398ChlorosuccinimideHCID 594970761-butyl-4-hydroxy-1H-pyridine-2-oneHCID 594970981-(Cyclopropylmethyl)-4-hydroxypyridin-2(1H)-one

Product 1

HCID 594970741-butyl-3-chloro-4-hydroxy-2(1H)-Pyridinone

Sources & evidence

ORD record
ord-59971408df414c75bb4fd5ae3fc8fde5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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