Chloroacetyl chloride → 1'-(Chloroacetyl)-spiro[isobenzofuran-1(3H),4'-piperidine]
Reaction equation
[CH2:15]([N:16]([CH:17]([CH3:18])[CH3:19])[CH:20]([CH3:21])[CH3:22])[CH3:23].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[Cl:24][CH2:25][C:26](=[O:27])[Cl:28].[NH:1]1[CH2:2][CH2:3][C:4]2([O:5][CH2:6][c:7]3[c:8]2[cH:9][cH:10][cH:11][cH:12]3)[CH2:13][CH2:14]1>>[N:1]1([C:26]([CH2:25][Cl:24])=[O:27])[CH2:2][CH2:3][C:4]2([O:5][CH2:6][c:7]3[c:8]2[cH:9][cH:10][cH:11][cH:12]3)[CH2:13][CH2:14]1Participants
5
Sources & evidence
- ORD record
- ord-c8d758cf7da1467589314d4aa3738755
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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