Hydrazine → HCID 86762669, compound

HRID 68560Notes

Reaction equation

HRID 68560 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH2:9][C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=O)=[CH:4][C:3]=1[CH3:19].[NH2:20][NH2:21]>C1COCC1>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[NH:21][N:20]=2)=[CH:4][C:3]=1[CH3:19]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 821204491-(4-Fluoro-3-methyl-phenyl)-3-phenyl-1,3-propanedione

Product 1

HCID 86762669HCID 86762669, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
75 °C

Procedure

1.7 g 1-(4-fluoro-3-methyl-phenyl)-3-phenyl-1,3-propanedione was dissolved in 20 mL of a solution of 1 N hydrazine in THF and stirred for 3 h at 75° C. The solvent was removed and the residue was crystallized to give 1.7 g of the desired compound.

Workup

  1. customThe solvent was removed
  2. customthe residue was crystallized

Sources & evidence

ORD record
ord-8f98da1caea741c3b1546aee72bc285b
Source dataset
uspto-grants-2014_09
Patent number
US08822464B2

Reaction notes

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