Hydrochloric Acid → 5-Chloro-6-{4-[6-(4-fluoro-phenyl)-2-(2-methyl-pyrrolidin-1-yl)-pyrimidin-4-yl]-piperazin-1-yl}-nicotinic acid
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[cH:6][n:7][c:8]([N:12]2[CH2:13][CH2:14][N:15]([c:18]3[n:19][c:20]([N:31]4[CH:32]([CH3:36])[CH2:33][CH2:34][CH2:35]4)[n:21][c:22](-[c:24]4[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]4)[cH:23]3)[CH2:16][CH2:17]2)[c:9]([Cl:11])[cH:10]1)=[O:37].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:39][CH2:40][OH:41].[ClH:42].[OH2:38]>>[O:3]=[C:4]([c:5]1[cH:6][n:7][c:8]([N:12]2[CH2:13][CH2:14][N:15]([c:18]3[n:19][c:20]([N:31]4[CH:32]([CH3:36])[CH2:33][CH2:34][CH2:35]4)[n:21][c:22](-[c:24]4[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]4)[cH:23]3)[CH2:16][CH2:17]2)[c:9]([Cl:11])[cH:10]1)[OH:37]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-94c751d3c6e7443387445fcd95e10d9e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…