Ammonium → tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate

HRID 686449Notes

Reaction equation

HRID 686449 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]2[O:11][CH:12]2[CH2:13]1.[CH3:21][OH:22].[Cl-:14].[N-:17]=[N+:18]=[N-:19].[NH4+:15].[Na+:16].[OH2:20]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([NH2:17])[CH:12]([OH:11])[CH2:13]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 887MethanolHCID 923Sodium ionHCID 962WaterHCID 33558AzideHCID 10103880tert-Butyl 6-Oxa-3-azabicyclo(3.1.0)hexane-3-carboxylate

Product 1

HCID 11229445tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-6156616ef9e54f18b364a10a2bd0d9bf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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