Tetrahydrofuran → 1-Cyclobutyl-4-(3-ethyl-5-methyl-2-naphthalen-1-yl-3H-imidazol-4-ylmethyl)-piperazine

HRID 686468Notes

Reaction equation

HRID 686468 reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:31][CH:32]([CH2:33][AlH:34][CH2:35][CH:36]([CH3:37])[CH3:38])[CH3:39].[CH:1]1([N:5]2[CH2:6][CH2:7][N:8]([C:11](=[O:12])[c:13]3[n:14]([CH2:29][CH3:30])[c:15](-[c:19]4[cH:20][cH:21][cH:22][c:23]5[cH:24][cH:25][cH:26][cH:27][c:28]45)[n:16][c:17]3[CH3:18])[CH2:9][CH2:10]2)[CH2:2][CH2:3][CH2:4]1>>[CH:1]1([N:5]2[CH2:6][CH2:7][N:8]([CH2:11][c:13]3[n:14]([CH2:29][CH3:30])[c:15](-[c:19]4[cH:20][cH:21][cH:22][c:23]5[cH:24][cH:25][cH:26][cH:27][c:28]45)[n:16][c:17]3[CH3:18])[CH2:9][CH2:10]2)[CH2:2][CH2:3][CH2:4]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 14487Diisobutylaluminum hydrideHCID 59338300HCID 59338300, compound

Product 1

HCID 593385021-Cyclobutyl-4-(3-ethyl-5-methyl-2-naphthalen-1-yl-3H-imidazol-4-ylmethyl)-piperazine

Sources & evidence

ORD record
ord-077f35f3ca4b482da6dbfa33846d7d25
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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