Dimethylformamide → N-[[4-[(3,4-dichlorophenyl)methyl]morpholin-2-yl]methyl]-2-(5-phenyltetrazol-2-yl)acetamide

HRID 686616Notes

Reaction equation

HRID 686616 reaction equation
[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[CH:16]([N:17]([CH2:18][CH3:19])[CH:20]([CH3:21])[CH3:22])([CH3:23])[CH3:24].[Cl:25][c:26]1[cH:27][c:28]([CH2:29][N:30]2[CH2:31][CH:32]([CH2:36][NH2:37])[O:33][CH2:34][CH2:35]2)[cH:38][cH:39][c:40]1[Cl:41].[c:1]1(-[c:7]2[n:8][n:9][n:10]([CH2:12][C:13](=[O:14])[OH:15])[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][n:9][n:10]([CH2:12][C:13](=[O:15])[NH:37][CH2:36][CH:32]3[CH2:31][N:30]([CH2:29][c:28]4[cH:27][c:26]([Cl:25])[c:40]([Cl:41])[cH:39][cH:38]4)[CH2:35][CH2:34][O:33]3)[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 10865632-(5-phenyl-2H-1,2,3,4-tetrazol-2-yl)acetic acidHCID 10308229[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine

Product 1

HCID 21962810N-[[4-[(3,4-dichlorophenyl)methyl]morpholin-2-yl]methyl]-2-(5-phenyltetrazol-2-yl)acetamide

Sources & evidence

ORD record
ord-253f4a91c04c49c085aed7141e6de0c0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…