Tetrahydrofuran → 2-Bromo-5-[3-{[tert-butyl(dimethyl)silyl]oxy}-2-({[tert-butyl(dimethyl)silyl]oxy}methyl)propoxy]pyridine
Reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([OH:29])[cH:27][n:28]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH:8]([CH2:9][OH:10])[CH2:11][O:12][Si:13]([CH3:14])([CH3:15])[C:16]([CH3:17])([CH3:18])[CH3:19])([CH3:20])[CH3:21].[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH:8]([CH2:9][O:10][c:26]1[cH:25][cH:24][c:23]([Br:22])[n:28][cH:27]1)[CH2:11][O:12][Si:13]([CH3:14])([CH3:15])[C:16]([CH3:17])([CH3:18])[CH3:19])([CH3:20])[CH3:21]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-572dc8a5baeb43e3ab909d09d9699614
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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