Isopropanol → 4-[(5,6-Dichloro-pyridazin-4-ylamino)-methyl]-piperidine-1-carboxylic acid benzyl ester
Reaction equation
[CH:10]([N:11]([CH2:12][CH3:13])[CH:14]([CH3:15])[CH3:16])([CH3:17])[CH3:18].[CH:37]([OH:38])([CH3:39])[CH3:40].[Cl:1][c:2]1[n:3][n:4][cH:5][c:6]([Cl:9])[c:7]1[Cl:8].[NH2:19][CH2:20][CH:21]1[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][CH2:30][c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH2:25][CH2:26]1>>[Cl:1][c:2]1[n:3][n:4][cH:5][c:6]([NH:19][CH2:20][CH:21]2[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][CH2:30][c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[CH2:25][CH2:26]2)[c:7]1[Cl:8]Participants
5
Sources & evidence
- ORD record
- ord-2da0700533f742cdb2773c6ff4af14f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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