Hydrochloric Acid → 6-[(5-Chloro-thiophen-2-yl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]4-(3-ethoxy-phenyl)-1H-quinolin-2-one

HRID 686781Notes

Reaction equation

HRID 686781 reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7]([OH:8])([c:9]2[n:10]([CH3:14])[cH:11][n:12][cH:13]2)[c:15]2[cH:16][c:17]3[c:18](-[c:27]4[cH:28][c:29]([O:33][CH2:34][CH3:35])[cH:30][cH:31][cH:32]4)[cH:19][c:20]([O:25][CH3:26])[n:21][c:22]3[cH:23][cH:24]2)[s:6]1.[ClH:36]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7]([OH:8])([c:9]2[n:10]([CH3:14])[cH:11][n:12][cH:13]2)[c:15]2[cH:16][c:17]3[c:18](-[c:27]4[cH:28][c:29]([O:33][CH2:34][CH3:35])[cH:30][cH:31][cH:32]4)[cH:19][c:20](=[O:25])[nH:21][c:22]3[cH:23][cH:24]2)[s:6]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 22465418(5-chloro-thiophen-2-yl)-[4-(3-ethoxy-phenyl)-2-methoxy-quinolin-6-yl]-(3-methyl-3H-imidazol-4-yl)-methanol

Product 1

HCID 224654066-[(5-Chloro-thiophen-2-yl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]4-(3-ethoxy-phenyl)-1H-quinolin-2-one

Sources & evidence

ORD record
ord-600d9a0067b0444a9b82a42464516c81
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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