Toluene → 4-bromo-N-(4-morpholin-4-ylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

HRID 688337Notes

Reaction equation

HRID 688337 reaction equation
[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[CH:29]([N:30]([CH:31]([CH3:32])[CH3:33])[CH2:34][CH3:35])([CH3:36])[CH3:37].[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[cH:8][cH:9][c:10]([NH:13][c:14]3[nH:15][c:16](=[O:23])[c:17]4[c:18]([n:19]3)[nH:20][cH:21][cH:22]4)[cH:11][cH:12]2)[CH2:5][CH2:6]1.[P:24]([Br:25])([Br:26])([Br:27])=[O:28]>>[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[cH:8][cH:9][c:10]([NH:13][c:14]3[n:15][c:16]([Br:26])[c:17]4[c:18]([n:19]3)[nH:20][cH:21][cH:22]4)[cH:11][cH:12]2)[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 24613Phosphorus oxybromideHCID 81531DiisopropylethylamineHCID 136176028HCID 136176028, compound

Product 1

HCID 579913094-bromo-N-(4-morpholin-4-ylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Sources & evidence

ORD record
ord-dda590bb233f41999700ea063e981cef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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