Dimethylformamide → N-(5-bromo-pyridin-2-yl)-2-methylsulfanyl-acetamide

HRID 688667Notes

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]([NH2:8])[n:6][cH:7]1.[CH3:42][S:43][CH2:44][C:45](=[O:46])[OH:47].[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[O:48]=[CH:49][N:50]([CH3:51])[CH3:52].[P-:9]([F:10])([F:11])([F:12])([F:13])([F:14])[F:15].[n:16]1([O:17][C:18]([N:19]([CH3:20])[CH3:21])=[N+:22]([CH3:23])[CH3:24])[c:25]2[n:26][cH:27][cH:28][cH:29][c:30]2[n:31][n:32]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:45]([CH2:44][S:43][CH3:42])=[O:46])[n:6][cH:7]1

Participants

Reactant 6

HCID 6228Dimethylformamide

HCID 9886Hexafluorophosphate

HCID 706222-Amino-5-bromopyridine

HCID 75551(Methylthio)acetic acid

HCID 81531Diisopropylethylamine

HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium

Product 1

HCID 60715941N-(5-bromo-pyridin-2-yl)-2-methylsulfanyl-acetamide

Sources & evidence

ORD record: ord-7e305b5cf2674ecabeac4493b6481a3b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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