Acetone → 2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)-5-(trifluoromethyl)phenyl]propan-2-ol
Reaction equation
[Br:1][c:2]1[cH:3][c:4](-[n:12]2[c:13]([CH3:18])[cH:14][cH:15][c:16]2[CH3:17])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[CH2:19]([Li:20])[CH2:21][CH2:22][CH3:23].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:24][C:25]([CH3:26])=[O:27].[CH3:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40].[Cl-:28].[NH4+:29]>>[c:2]1([C:25]([CH3:24])([CH3:26])[OH:27])[cH:3][c:4](-[n:12]2[c:13]([CH3:18])[cH:14][cH:15][c:16]2[CH3:17])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
8
Sources & evidence
- ORD record
- ord-a25e6559706c4d5f976a9106a6c1ea53
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…