Tetrahydrofuran → 3-Dipropylamino-5-acetylchroman

HRID 689648Notes

Reaction equation

HRID 689648 reaction equation
[CH2:1]([CH2:2][CH3:3])[N:4]([CH:5]1[CH2:6][O:7][c:8]2[cH:9][cH:10][cH:11][c:12]([C:15]([O:17][CH3:16])=[O:18])[c:13]2[CH2:14]1)[CH2:19][CH2:20][CH3:21].[CH3:22][Li:23].[Cu:29][I:30].[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1>>[CH2:1]([CH2:2][CH3:3])[N:4]([CH:5]1[CH2:6][O:7][c:8]2[cH:9][cH:10][cH:11][c:12]([C:15](=[O:17])[CH3:22])[c:13]2[CH2:14]1)[CH2:19][CH2:20][CH3:21]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 190280933-Dipropylamino-5-methyloxycarbonylchromanHCID 178418348HCID 178418348, compound

Product 1

HCID 102212133-Dipropylamino-5-acetylchroman

Sources & evidence

ORD record
ord-cb59892303e44cf09e8e5cbf3cefd88a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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