Hydrochloric Acid → 1'-Benzyl-6-chloro-3H-spiro[isobenzofuran-1,4'-piperidine]
Reaction equation
[BH3:24].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([O:12][C:13](=[O:21])[c:14]3[c:15]2[cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[CH2:22][CH2:23]1.[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[ClH:25].[Na+:27].[OH-:26]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([O:12][CH2:13][c:14]3[c:15]2[cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[CH2:22][CH2:23]1Participants
7
Sources & evidence
- ORD record
- ord-241c9f57c72f4eb5b2f3bcd8cb27bd9b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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