Hydrochloric Acid → 8-(5-Fluoro-2-methylphenoxymethyl)-7-(4-hydroxy-2-methoxyphenyl)-1,3,3-trimethyl-3,4-dihydro-1H-quinoxalin-2-one

HRID 691093Notes

Reaction equation

HRID 691093 reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][O:48][CH2:49]1.[CH3:50][OH:51].[CH3:52][CH2:53][O:54][C:55](=[O:56])[CH3:57].[ClH:43].[F:1][c:2]1[cH:3][cH:4][c:5]([CH3:36])[c:6]([O:7][CH2:8][c:9]2[c:10](-[c:23]3[c:24]([O:33][CH3:34])[cH:25][c:26]([O:29][CH2:30][O:31][CH3:32])[cH:27][cH:28]3)[cH:11][cH:12][c:13]3[c:18]2[N:17]([CH3:19])[C:16](=[O:20])[C:15]([CH3:21])([CH3:22])[NH:14]3)[cH:35]1.[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH3:36])[c:6]([O:7][CH2:8][c:9]2[c:10](-[c:23]3[c:24]([O:33][CH3:34])[cH:25][c:26]([OH:29])[cH:27][cH:28]3)[cH:11][cH:12][c:13]3[c:18]2[N:17]([CH3:19])[C:16](=[O:20])[C:15]([CH3:21])([CH3:22])[NH:14]3)[cH:35]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 8857Ethyl AcetateHCID 312751,4-Dioxane2×HCID 583371898-(5-Fluoro-2-methylphenoxymethyl)-7-(2-methoxy-4-methoxymethoxyphenyl)-1,3,3-trimethyl-3,4-dihydro-1H-quinoxalin-2-one

Product 1

HCID 252112638-(5-Fluoro-2-methylphenoxymethyl)-7-(4-hydroxy-2-methoxyphenyl)-1,3,3-trimethyl-3,4-dihydro-1H-quinoxalin-2-one

Sources & evidence

ORD record
ord-2776aac9b764437db13d21005deff818
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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