Tetrahydrofuran → 2-(2-Chloro-4-fluorophenyl)ethan-1-amine
Reaction equation
[Al+3:14].[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[Cl:1][c:2]1[c:3]([CH2:9][C:10](=[O:11])[NH2:12])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[H-:13].[H-:16].[H-:17].[H-:18].[Li+:15]>>[Cl:1][c:2]1[c:3]([CH2:9][CH2:10][NH2:12])[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-5dc7ac8498e847d59c178a4b5332e964
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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