Tetrahydrofuran → 5-Chloro-1H-pyrrolo[2,3-b]pyridine

HRID 691149Notes

Reaction equation

HRID 691149 reaction equation
[CH2:19]([N+:20]([CH2:21][CH2:22][CH2:23][CH3:24])([CH2:25][CH2:26][CH2:27][CH3:28])[CH2:29][CH2:30][CH2:31][CH3:32])[CH2:33][CH2:34][CH3:35].[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][c:9]([Si:11]([CH2:12][CH3:13])([CH2:14][CH3:15])[CH2:16][CH3:17])[cH:10]2.[F-:18]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][cH:10]2

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 57774343HCID 57774343, compound

Product 1

HCID 242292135-Chloro-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record
ord-5b5c5c3d991e4aa7ad9e4963980ff647
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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