Tetrahydrofuran → 2-(2,4-Difluorophenyl)-3-methyl-3-(pyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Reaction equation
[CH3:1][CH:2]([CH3:3])[c:4]1[n:5][cH:6][n:7][cH:8][cH:9]1.[CH:10]([N-:11][CH:12]([CH3:13])[CH3:14])([CH3:15])[CH3:16].[F:18][c:19]1[c:20]([C:26]([CH2:27][n:28]2[n:29][cH:30][n:31][cH:32]2)=[O:33])[cH:21][cH:22][c:23]([F:25])[cH:24]1.[Li+:17].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[CH3:1][C:2]([CH3:3])([c:4]1[n:5][cH:6][n:7][cH:8][cH:9]1)[C:26]([c:20]1[c:19]([F:18])[cH:24][c:23]([F:25])[cH:22][cH:21]1)([CH2:27][n:28]1[n:29][cH:30][n:31][cH:32]1)[OH:33]Participants
6
Sources & evidence
- ORD record
- ord-1ef0f83dd42a4833b67e36bfc84c7361
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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