Hydrochloric Acid → 2-({[6-Butyl-5-(4-cyclohexyloxy-phenyl)-pyridazine-3-carbonyl]-amino}-methyl)-morpholine-4-carboxylic acid tert-butyl ester
Reaction equation
[C:45]([CH3:46])([CH3:47])([CH3:48])[O:49][C:50](=[O:51])[N:52]1[CH2:53][CH:54]([CH2:58][NH2:59])[O:55][CH2:56][CH2:57]1.[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[ClH:1].[F:2][c:3]1[c:4]([O:9][C:10](=[O:5])[c:12]2[n:13][n:14][c:15]([CH2:31][CH2:32][CH2:33][CH3:34])[c:16](-[c:18]3[cH:19][cH:20][c:21]([O:24][CH:25]4[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]4)[cH:22][cH:23]3)[cH:17]2)[c:6]([F:7])[c:8]([F:11])[c:35]([F:36])[c:37]1[F:38].[cH:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1>>[O:9]=[C:10]([c:12]1[n:13][n:14][c:15]([CH2:31][CH2:32][CH2:33][CH3:34])[c:16](-[c:18]2[cH:19][cH:20][c:21]([O:24][CH:25]3[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]3)[cH:22][cH:23]2)[cH:17]1)[NH:59][CH2:58][CH:54]1[CH2:53][N:52]([C:50]([O:49][C:45]([CH3:46])([CH3:47])[CH3:48])=[O:51])[CH2:57][CH2:56][O:55]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-82f9135723b9490484d2d8a62e907b2f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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