Dimethyl Sulfoxide → 4-(5-(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde

HRID 692951Notes

Reaction equation

HRID 692951 reaction equation
[CH3:7][S:8](=[O:9])[CH3:10].[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[c:11]1(-[n:17]2[n:18][cH:19][c:20](-[c:26]3[n:27][c:28](-[c:31]4[cH:32][cH:33][c:34]([CH2:37][OH:38])[cH:35][cH:36]4)[n:29][o:30]3)[c:21]2[C:22]([F:23])([F:24])[F:25])[cH:12][cH:13][cH:14][cH:15][cH:16]1>>[c:11]1(-[n:17]2[n:18][cH:19][c:20](-[c:26]3[n:27][c:28](-[c:31]4[cH:32][cH:33][c:34]([CH:37]=[O:38])[cH:35][cH:36]4)[n:29][o:30]3)[c:21]2[C:22]([F:23])([F:24])[F:25])[cH:12][cH:13][cH:14][cH:15][cH:16]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 65578Oxalyl chlorideHCID 81531DiisopropylethylamineHCID 66996273(4-(5-(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)phenyl)methanol

Product 1

HCID 866590404-(5-(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde

Sources & evidence

ORD record
ord-b860d46ca5a8461d8bd9f150d5ffe071
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…