Bicarbonate Ion → 1-[3-(4-(5-fluoro-3-indolyl)-1,2,3,6-tetrahydro-1-pyridyl)propyl]-5,6-dihydro(1H,4H)-1,2,5-thiadiazolo[4,3,2-ij]quinoline 2,2-dioxide

HRID 693329Notes

Reaction equation

HRID 693329 reaction equation
[C:35](=[O:36])([OH:37])[O-:38].[CH3:40][N:41]([CH3:42])[CH:43]=[O:44].[Cl:1][CH2:2][CH2:3][CH2:4][N:5]1[S:6](=[O:17])(=[O:18])[N:7]2[CH2:8][CH2:9][CH2:10][c:11]3[cH:12][cH:13][cH:14][c:15]1[c:16]32.[F:19][c:20]1[cH:21][c:22]2[c:23]([C:29]3=[CH:34][CH2:33][NH:32][CH2:31][CH2:30]3)[cH:24][nH:25][c:26]2[cH:27][cH:28]1.[Na+:39].[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1>>[CH2:2]([CH2:3][CH2:4][N:5]1[S:6](=[O:17])(=[O:18])[N:7]2[CH2:8][CH2:9][CH2:10][c:11]3[cH:12][cH:13][cH:14][c:15]1[c:16]32)[N:32]1[CH2:31][CH2:30][C:29]([c:23]2[c:22]3[cH:21][c:20]([F:19])[cH:28][cH:27][c:26]3[nH:25][cH:24]2)=[CH:34][CH2:33]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 113449595-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 198884501-(3-chloropropyl)-5,6-dihydro(1H,4H)-1,2,5-thiadiazolo[4,3,2-ij]quinoline 2,2-dioxide

Product 1

HCID 198884641-[3-(4-(5-fluoro-3-indolyl)-1,2,3,6-tetrahydro-1-pyridyl)propyl]-5,6-dihydro(1H,4H)-1,2,5-thiadiazolo[4,3,2-ij]quinoline 2,2-dioxide

Sources & evidence

ORD record
ord-24d5797422f9477faec8a449b6131059
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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