Dimethyl Sulfide → tert-butyl N-[3-(hydroxymethyl)cyclohexyl]carbamate

HRID 693590Notes

Reaction equation

[BH3:21].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][CH:11]([C:15](=[O:16])[OH:17])[CH2:12][CH2:13][CH2:14]1.[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[CH3:18][S:19][CH3:20]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][CH:11]([CH2:15][OH:16])[CH2:12][CH2:13][CH2:14]1

Participants

Reactant 4

HCID 1068Dimethyl Sulfide

HCID 6331Borane

HCID 8028Tetrahydrofuran

HCID 44203163-(((Tert-butoxy)carbonyl)amino)cyclohexane-1-carboxylic acid

Product 1

HCID 22106830tert-butyl N-[3-(hydroxymethyl)cyclohexyl]carbamate

Sources & evidence

ORD record: ord-213f681eb2e84f42a15dfab1574870a2
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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