Water → tert-Butyl (4-(2-hydroxyethyl)pyridin-2-yl)carbamate

HRID 694138Notes

Reaction equation

HRID 694138 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[n:10][cH:11][cH:12][c:13]([CH2:15][C:16](=[O:17])[O:18][CH2:19][CH3:20])[cH:14]1.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:21][CH:22]([CH2:23][AlH:24][CH2:25][CH:26]([CH3:27])[CH3:28])[CH3:29].[OH2:30]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[n:10][cH:11][cH:12][c:13]([CH2:15][CH2:16][OH:17])[cH:14]1

Participants

5

Reactant 4

HCID 962WaterHCID 8028TetrahydrofuranHCID 14487Diisobutylaluminum hydrideHCID 53419364(2-Boc-amino-pyridin-4-yl)-acetic acid ethyl ester

Product 1

HCID 58416767tert-Butyl (4-(2-hydroxyethyl)pyridin-2-yl)carbamate

Sources & evidence

ORD record
ord-4f6d0dde5e4840809ac3dc5c16703338
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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