Methyl iodide → 5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(2,4-dimethoxyphenyl)methyl]-3-methylpiperidin-2-one
Reaction equation
[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:36][Si:37]([N-:38][Si:39]([CH3:40])([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[CH2:9][CH2:10][C:11](=[O:32])[N:12]([CH2:21][c:22]3[c:23]([O:30][CH3:31])[cH:24][c:25]([O:28][CH3:29])[cH:26][cH:27]3)[CH:13]2[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:5][cH:6][cH:7]1.[I:33][CH3:34].[Li+:35]>>[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[CH2:9][CH:10]([CH3:36])[C:11](=[O:32])[N:12]([CH2:21][c:22]3[c:23]([O:30][CH3:31])[cH:24][c:25]([O:28][CH3:29])[cH:26][cH:27]3)[CH:13]2[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:5][cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-2251daff89ca4f56ad2ae1614057b782
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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