Dimethylformamide → 2-[3-(4-Fluoro-benzoylamino)-phenyl]-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid

HRID 694652Notes

Reaction equation

HRID 694652 reaction equation
[C:11]([n:12]1[cH:13][cH:14][n:15][cH:16]1)([n:17]1[cH:18][cH:19][n:20][cH:21]1)=[O:22].[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[F:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1.[NH2:23][c:24]1[cH:25][c:26]([CH:30]2[NH:31][c:32]3[cH:33][cH:34][c:35]([C:42](=[O:43])[OH:44])[cH:36][c:37]3[CH2:38][C:39]2([CH3:40])[CH3:41])[cH:27][cH:28][cH:29]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[NH:23][c:24]2[cH:25][c:26]([CH:30]3[NH:31][c:32]4[cH:33][cH:34][c:35]([C:42](=[O:43])[OH:44])[cH:36][c:37]4[CH2:38][C:39]3([CH3:40])[CH3:41])[cH:27][cH:28][cH:29]2)[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 99734-Fluorobenzoic AcidHCID 682631,1'-CarbonyldiimidazoleHCID 67441465HCID 67441465, compound

Product 1

HCID 674417432-[3-(4-Fluoro-benzoylamino)-phenyl]-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid

Sources & evidence

ORD record
ord-22669c2caaa445aaa8adda368896e9f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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