Diethyl Ether → Tert-butyl 4-{3-[6-amino-5-chloro-2-(methyloxy)-3-pyridinyl]-3-oxopropyl}-1-piperidinecarboxylate
Reaction equation
[CH2:40]([O:41][CH2:42][CH3:43])[CH3:44].[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[Cl:27][N:28]1[C:29](=[O:30])[CH2:31][CH2:32][C:33]1=[O:34].[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:10]([CH2:11][CH2:12][CH:13]2[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]2)=[O:26])[c:6]([O:8][CH3:9])[n:7]1>>[NH2:1][c:2]1[c:3]([Cl:27])[cH:4][c:5]([C:10]([CH2:11][CH2:12][CH:13]2[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]2)=[O:26])[c:6]([O:8][CH3:9])[n:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f71d2aa2168d48888596c3da7162cdf6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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