Bicarbonate Ion → tert-butyl 5-(2-(3-(2-chloroacetamido)phenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate
Reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:50][CH2:51][O:52][C:53]([CH3:54])=[O:55].[Cl:45][CH2:46][C:47](=[O:48])[Cl:49].[NH2:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]3[c:16]([NH:18][c:19]3[cH:20][c:21]4[cH:22][n:23][n:24]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[c:25]4[cH:26][cH:27]3)[n:17]2)[cH:5][cH:6][cH:7]1.[Na+:44].[O-:40][C:41]([OH:42])=[O:43]>>[NH:1]([c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]3[c:16]([NH:18][c:19]3[cH:20][c:21]4[cH:22][n:23][n:24]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[c:25]4[cH:26][cH:27]3)[n:17]2)[cH:5][cH:6][cH:7]1)[C:47]([CH2:46][Cl:45])=[O:48]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a3c60ffede48416c8a93c6b6a0e1cc20
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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