1,2-Dichloroethane → Tert-butyl 3-(isoquinolin-6-ylamino)-3-oxo-2-(4-((triisopropylsilyloxy)methyl)phenyl)propyl(methyl)carbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH2:9][CH:10]([C:11](=[O:12])[OH:13])[c:14]1[cH:15][cH:16][c:17]([CH2:20][O:21][Si:22]([CH:23]([CH3:24])[CH3:25])([CH:26]([CH3:27])[CH3:28])[CH:29]([CH3:30])[CH3:31])[cH:18][cH:19]1)[CH3:32].[CH2:33]([Cl:34])[CH2:35][Cl:36].[CH3:54][N:55]([c:56]1[cH:57][cH:58][n:59][cH:60][cH:61]1)[CH3:62].[NH2:37][c:38]1[cH:39][c:40]2[cH:41][cH:42][n:43][cH:44][c:45]2[cH:46][cH:47]1.[cH:48]1[cH:49][cH:50][n:51][cH:52][cH:53]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH2:9][CH:10]([C:11](=[O:13])[NH:37][c:38]1[cH:39][c:40]2[cH:41][cH:42][n:43][cH:44][c:45]2[cH:46][cH:47]1)[c:14]1[cH:15][cH:16][c:17]([CH2:20][O:21][Si:22]([CH:23]([CH3:24])[CH3:25])([CH:26]([CH3:27])[CH3:28])[CH:29]([CH3:30])[CH3:31])[cH:18][cH:19]1)[CH3:32]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-449b80fd68a6498baa4b738ee97ab559
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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