Acetic Acid → N-(2-Chloro-4-((6-cyano-7-((1-methyl-4-piperidyl)methoxy)-4-quinolyl)oxy)phenyl)-N'-cyclopropylurea
Reaction equation
[C:42]([BH3-:43])#[N:44].[C:46](=[O:47])([OH:48])[O-:49].[CH2:36]=[O:37].[CH3:38][C:39](=[O:40])[OH:41].[CH3:56][CH2:57][O:58][C:59](=[O:60])[CH3:61].[Cl:1][c:2]1[c:3]([NH:29][C:30](=[O:31])[NH:32][CH:33]2[CH2:34][CH2:35]2)[cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][cH:11][n:12][c:13]3[cH:14][c:15]([O:21][CH2:22][CH:23]4[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]4)[c:16]([C:19]#[N:20])[cH:17][c:18]23)[cH:7]1.[Na+:45].[Na+:50].[O:51]1[CH2:52][CH2:53][CH2:54][CH2:55]1>>[Cl:1][c:2]1[c:3]([NH:29][C:30](=[O:31])[NH:32][CH:33]2[CH2:34][CH2:35]2)[cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][cH:11][n:12][c:13]3[cH:14][c:15]([O:21][CH2:22][CH:23]4[CH2:24][CH2:25][N:26]([CH3:38])[CH2:27][CH2:28]4)[c:16]([C:19]#[N:20])[cH:17][c:18]23)[cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-525a017f22394e1dbc878815282a6d5f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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